Effect of gut microbiota on production traits, interaction with genetics

Autor: Hélène Gilbert, Sandrine Lagarrigue, Verschuren, L. M. G., Olivier Zemb, Velasco, M., Jean-Luc Gourdine, Bergsma, R., David Renaudeau, Sanchez, J. P., Hervé Garreau
Přispěvatelé: Génétique Physiologie et Systèmes d'Elevage (GenPhySE ), Institut National de la Recherche Agronomique (INRA)-Ecole Nationale Vétérinaire de Toulouse (ENVT), Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Université de Toulouse (UT)-École nationale supérieure agronomique de Toulouse (ENSAT), Université de Toulouse (UT)-Université de Toulouse (UT), Physiologie, Environnement et Génétique pour l'Animal et les Systèmes d'Elevage [Rennes] (PEGASE), Institut National de la Recherche Agronomique (INRA)-AGROCAMPUS OUEST, Topigs Norsvin Research Center B.V., Schoenaker, Partenaires INRAE, Institut de Recerca i Tecnologia Agroalimentàries = Institute of Agrifood Research and Technology (IRTA), Unité de Recherches Zootechniques (URZ), Institut National de la Recherche Agronomique (INRA), European Union’s H2020 Feed-a-Gene Project (grant 633531, European Project: 633531,H2020,H2020-SFS-2014-2,Feed-a-Gene(2015), École nationale supérieure agronomique de Toulouse [ENSAT]-Institut National de la Recherche Agronomique (INRA)-Ecole Nationale Vétérinaire de Toulouse (ENVT), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National Polytechnique (Toulouse) (Toulouse INP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), Institute of Agrifood Research and Technology (IRTA)
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Annual Meeting of the European Association for Animal Production
69. Annual Meeting of the European Association of Animal Production
69. Annual Meeting of the European Association of Animal Production, Aug 2018, Dubrovnik, Croatia. 705 p
HAL
Book of Abstracts of the 69th Annual Meeting of the European Federation of Animal Science. 1ère Ed. (24), 2018; 69. Annual Meeting of the European Association of Animal Production, Dubrovnik, HRV, 2018-08-27-2018-08-31, 204-204
Popis: International audience; Gut microbiota is a key contributor to feed use in monogastric species, in particular via the digestion dietary fibres. Molecular techniques are now available to run large studies and decipher the potential of gut microbiota to improve livestock. Studies on human and mice are more advanced: different factors have been demonstrated to influence the gut microbiota composition and functions, including maternal transmission, environment (diet composition and quantity, humidity and heat), age and physiological status. Studies also evaluated if the host controls its gut microbiota. In pigs, chicken and rabbits, microbiota differences between animals of extreme phenotypes within populations, and between lines divergently selected for specific traits, are reported. Other studies reported that some microbiota abundancies are heritable. Linear mixed models have been used to evaluate its contribution to trait variability, or microbiability, with different data (full vs 16S sequencing of gut or faecal contents) and different variance matrices. They showed significant contribution to production traits, reaching more than 30%. However, confounding effects exist, such as the maternal inheritance of the microbiota and the genetic determinism by the host : many studies show reduction of the genetic additive variance, in addition to reduction of the residual variance with microbiability. Specific datasets, testing a given genetic in different environments or using cross-fostering, are used to better understand the relative contribution of each effect (host genetics and microbiota) to the trait variance, and propose solutions to livestock.
Databáze: OpenAIRE
Externí odkaz: