| Autor: |
A. Talenti, S. Frattini, MASTRANGELO, Salvatore, DI GERLANDO, Rosalia, PORTOLANO, Baldassare, E. Lasagna, F. Sarti, M. Milanesi, L. Colli, E. Ciani, D. Soglia, S. Sartore, R. Ciampolini, A. Crisà, R. Steri, G. Catillo, D. Marletta, S. Bordonaro, M. D’Andrea, A. Chessa, B. Castiglioni, P. Loi, T. Sechi, A. Carta, R. Negrini, A. Stella, A. Valentini, F. Panella, G. Pagnacco, F. Pilla, P. Ajmone Marsan, P. Crepaldi . |
| Přispěvatelé: |
A. Talenti, S. Frattini, S. Mastrangelo, R. Di Gerlando, B. Portolano, E. Lasagna, F. Sarti, M. Milanesi, L. Colli, E. Ciani, D. Soglia, S. Sartore, R. Ciampolini, A. Crisà, R. Steri, G. Catillo, D. Marletta, S. Bordonaro, M. D’Andrea, A. Chessa, B. Castiglioni, P. Loi, T. Sechi, A. Carta, R. Negrini, A. Stella, A. Valentini, F. Panella, G. Pagnacco, F. Pilla, P. Ajmone Marsan, P. Crepaldi . |
| Jazyk: |
angličtina |
| Rok vydání: |
2017 |
| Předmět: |
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| Popis: |
The Italian Goat Consortium (IGC), joined the effort of many Universities and Research Institutes, in a comprehensive study of the Italian goat population genetic makeup using a medium density (54K) SNPs chip. Currently IGC has genotyped more than 1,000 animals from more than 30 goat breeds and populations from all Italian geographical and agroecological areas of goat rearing. The aim of this work is to obtain a clear picture of the Italian caprine biodiversity, to reconstruct the ancestry, to disentangle the genetic background and to assess the relationships among and within the investigated breeds. To date, the IGC dataset includes about 50 million genotypes. The data were quality checked by excluding markers and individuals on the basis of missing genotypes, minor allele frequency and close individual relatedness. Genetic relationships among and within breeds was investigated by Multi-Dimensional Scaling and Principal Component Analysis. Population structure, ancestry models and admixture were estimated by ADMIXTURE and fastSTRUCTURE software. Finally, phylogenic trees were reconstructed with PHYLIP software suite starting from shared-allele identity by state, and Reynolds distance matrices, while past migration events were modeled with TreeMix software. The results confirmed high levels of genetic polymorphism and confirmed the North-South geographical pattern of diversity, previously reported on a smaller sample of Italian goat breeds. The analysis also revealed a pivotal role of Central Italy in connecting the genetic resources of the northern and southern areas of the country, and confirms the genetic isolation of insular breeds. Moreover, some breeds show clearly distinctive and homogeneous gene pools, whereas other breeds present complex and, in some cases, dishomogeneous genetic background. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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