Seasonal variations of dioxine-like activity in sediments of the Bizerta lagoon (Tunisia) detected with in vitro cellular bioassays
| Autor: | Louiz, I., Ben-Hassine, O.K., Ben-Attia, M., Kinani, Saïd, Ait-Aissa, Selim |
|---|---|
| Přispěvatelé: | Unité de recherche Biologie, Ecologie et Parasitologie des Organisme Aquatiques, Faculté des Sciences Mathématiques, Physiques et Naturelles de Tunis (FST), Université de Tunis El Manar (UTM)-Université de Tunis El Manar (UTM), Laboratoire des mécanismes réactionnels (DCMR), École polytechnique (X)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Institut National de l'Environnement Industriel et des Risques (INERIS), Civs, Gestionnaire |
| Jazyk: | angličtina |
| Rok vydání: | 2010 |
| Předmět: | |
| Zdroj: | 39. CIESM Congress 39. CIESM Congress, May 2010, Venise, Italy |
| Popis: | In order to evaluate sediment contamination in six stations from Bizerta lagoon, a combination of in vitro bioassays and chemical analysis was applied to sediment organic extracts. By using 7- ethoxyresorufin-O-deethylase (EROD) induction in the fish hepatoma cell line PLHC-1 after 4 h of cell exposure, dioxin-like activities were detected in all analysed samples. Dioxin-like activities were higher in winter than in summer. A highly significant correlation was observed between bioassay- and chemical analyses-derived toxic equivalents (TEQs), but PAHs accounted for only a small part of the detected biological activities. Our results suggest the presence of unknown readily metabolised EROD inducing compounds, which will need to be further characterized |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|