The oxidative phosphorylation system in Mammalian mitochondria

Autor:	Papa S, Martino PL, Capitanio G, Gaballo A, DeRasmo D, Signorile A, Petruzzella V.
Jazyk:	angličtina
Rok vydání:	2012
Předmět:	inorganic chemicals enzymes and coenzymes (carbohydrates) bacteria macromolecular substances environment and public health
Zdroj:	pp. 3–37, 2012 info:cnr-pdr/source/autori:Papa S; Martino PL; Capitanio G; Gaballo A; De Rasmo D; Signorile A; Petruzzella V./titolo:The oxidative phosphorylation system in Mammalian mitochondria./titolo_volume:/curatori_volume:/editore:/anno:2012 info:cnr-pdr/source/autori:Papa S, Martino PL, Capitanio G, Gaballo A, DeRasmo D, Signorile A, Petruzzella V./titolo:The oxidative phosphorylation system in mammalian mitochondria./titolo_volume:/curatori_volume:/editore:/anno:2012
Popis:	The chapter provides a review of the state of art of the oxidative phosphorylation system in mammalian mitochondria. The sections of the paper deal with: (i) the respiratory chain as a whole: redox centers of the chain and protonic coupling in oxidative phosphorylation (ii) atomic structure and functional mechanism of protonmotive complexes I, III, IV and V of the oxidative phosphorylation system (iii) biogenesis of oxidative phosphorylation complexes: mitochondrial import of nuclear encoded subunits, assembly of oxidative phosphorylation complexes, transcriptional factors controlling biogenesis of the complexes. This advanced knowledge of the structure, functional mechanism and biogenesis of the oxidative phosphorylation system provides a background to understand the pathological impact of genetic and acquired dysfunctions of mitochondrial oxidative phosphorylation.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::46da02647ec36249a9acc480718dc396 https://publications.cnr.it/doc/174308 Zobrazit plný text záznamu