Regeneration of rat sciatic nerve using tubulation and allogeneic transplantation of adipose-derived mesenchymal stromal cells

Autor: Masgutov R., Masgutova G., Rogojin A., Zhuravleva M., Zakirova E., Nigmetzyanova M., Mukhametova L., Shulman A., Mukhamedshina Y., Yafarova G., Rizvanov A.
Rok vydání: 2016
Předmět:
Zdroj: SCOPUS23131829-2016-10-3-SID84961727470
Popis: The effectiveness of application of biodegradable conduit (NeuraGen; INTEGRA, USA) in combination with adipose derived multipotent mesenchymal stem cells and fibrin sealant (Tissucol-Kit; Baxter AG, Austria) on posttraumatic peripheral nerve regeneration was investigated using a rat model of sciatic nerve injury. We demonstrate that our proposed cell therapy confers a neuroprotective effect under our experimental design.
Databáze: OpenAIRE