Sarcoidosis occuring during anti-TNF-alpha treatment for inflammatory rheumatic diseases: report of two cases
| Autor: | Toussirot , E., Pertuiset , E., Kantelip , B., Wendling , D. |
|---|---|
| Přispěvatelé: | Institut de biologie et chimie des protéines [Lyon] (IBCP), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS), Agents pathogènes et inflammation - UFC (EA 4266) (API), Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC), Carcinogénèse épithéliale : facteurs prédictifs et pronostiques - UFC (EA 3181) (CEF2P / CARCINO), Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon)-Université de Franche-Comté (UFC), Service de Rhumatologie, Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon), Humbert, Murielle, Institut de biologie et chimie des protéines [Lyon] ( IBCP ), Université Claude Bernard Lyon 1 ( UCBL ), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique ( CNRS ), Agents pathogènes et inflammation - UFC (EA 4266) ( API ), Université de Franche-Comté ( UFC ), Carcinogénèse épithéliale : facteurs prédictifs et pronostiques - UFC ( CEF2P / CARCINO ), Université Bourgogne Franche-Comté ( UBFC ) -Université de Franche-Comté ( UFC ) -Centre Hospitalier Régional Universitaire [Besançon] ( CHRU Besançon ), Centre Hospitalier Régional Universitaire [Besançon] ( CHRU Besançon ) -Hôpital Jean Minjoz |
| Jazyk: | angličtina |
| Rok vydání: | 2008 |
| Předmět: |
MESH: Sarcoidosis
MESH: Antirheumatic Agents MESH : Immunoglobulin G MESH: Granuloma MESH : Male MESH : Rheumatic Diseases MESH : Sarcoidosis MESH: Antibodies Monoclonal MESH: Rheumatic Diseases [ SDV.MHEP.RSOA ] Life Sciences [q-bio]/Human health and pathology/Rhumatology and musculoskeletal system MESH: Lung Diseases MESH: Lymphatic Diseases MESH : Middle Aged MESH : Female MESH : Tumor Necrosis Factor-alpha MESH : Granuloma MESH: Immunoglobulin G [SDV.MHEP.RSOA] Life Sciences [q-bio]/Human health and pathology/Rhumatology and musculoskeletal system MESH: Middle Aged MESH: Humans MESH : Lung Diseases MESH : Lymphatic Diseases MESH : Humans MESH: Adult MESH : Adult MESH: Receptors Tumor Necrosis Factor MESH : Antirheumatic Agents MESH : Receptors Tumor Necrosis Factor MESH: Male [SDV.MHEP.RSOA]Life Sciences [q-bio]/Human health and pathology/Rhumatology and musculoskeletal system MESH : Antibodies Monoclonal MESH: Tumor Necrosis Factor-alpha MESH: Female |
| Zdroj: | Clinical and experimental rheumatology Clinical and experimental rheumatology, Clinical and Experimental Rheumatology Sas, 2008, 26 (3), pp.471-5 |
| ISSN: | 0392-856X |
| Popis: | International audience; Anti-TNF-alpha agents have been tried in cases of refractory sarcoidosis, giving favourable results. Thus, the occurrence of a granulomatous disease in a patient receiving such drug seems paradoxical. We describe 2 patients with inflammatory rheumatic disease, the first with ankylosing spondylitis, the second with rheumatoid arthritis, under anti-TNF-alpha treatment (infliximab and etanercept respectively) who developed non-caseating granulomas of the lungs and lymph nodes consistent with the diagnosis of sarcoidosis. Limited and various similar cases have been reported. It is generally considered that these granulomatous diseases are related to the anti-TNF-alpha agent. |
| Databáze: | OpenAIRE |
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