Changes of Branched Chain Amino Acids and Tyrosine Ratio (BTR) after Hepatectomy
| Autor: | Nanashima, Atsushi, Yamaguchi, Hiroyuki, Shibasaki, Shinichi, Abo, Takafumi, Morino, Shigeyuki, Yoshinaga, Megumi, Sawai, Terumitsu, Tanaka, Kenji, Hidaka, Shigekazu, Tsuji, Takashi, Nakagoe, Tohru, Ayabe, Hiroyoshi |
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| Jazyk: | angličtina |
| Rok vydání: | 2003 |
| Předmět: | |
| Zdroj: | Acta medica Nagasakiensia. 48(1-2):29-33 |
| ISSN: | 0001-6055 |
| Popis: | To clarify the clinical usefulness of measuring branched chain amino acids and tyrosine ratio (BTR), which is correlated with Fischer's ratio, we examined the serum BTR level in 33 patients with liver diseases. Serum levels of branched-chain amino acids (BCAAs) and tyrosine were measured by the new enzymatic method, which costs inexpensive and is immediate compared to measuring Fischer's ratio. BTR was calculated as ratio of concentration of BCAA to tyrosine. BTR was correlated with levels of albumin, transaminase and cholinesterase and was lower in patients with chronic viral hepatitis, Child B cirrhosis and portal hypertension. In 19 patients who underwent hepatic resection included 8 for major hepatectomy, resected volume, blood loss, operation time and background of liver diseases were not associated with changes of BTR after hepatectomy. In patients with prolonged jaundice, postoperative BTR level was significantly lower between day I and 7 after hepatectomy. We concluded that serum BTR level was correlated with poor liver function and monitoring of BTR levels after hepatectomy may be useful to evaluate degree of hepatic damage after liver surgery. Acta medica Nagasakiensia. 2003, 48(1-2), p.29-33 |
| Databáze: | OpenAIRE |
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