| Autor: |
Iiro Matti Aleksi Kiiski, Sanna Artes, Ville Jokinen, Päivi Järvinen, Tiina Marjukka Sikanen |
| Přispěvatelé: |
Division of Pharmaceutical Chemistry and Technology, Tiina Sikanen / Chemical Microsystems Lab, Drug Research Program |
| Předmět: |
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| Zdroj: |
University of Helsinki |
| Popis: |
We describe a microfluidic immobilized enzyme reactor that facilitates the screening of complex drug-drug interactions involving several different drug-metabolizing enzymes, and thus offers a comprehensive tool for in vitro prediction of a drug's metabolic clearance in vivo. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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