Prevalencija sustavnih bolesti i lijekova u bolesnika s oralnim lihenom planusom
Autor: | Canjuga, Ivana, Marinka Mravak-Stipetić, Loncar, Bozana, Kern, Josipa |
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Jazyk: | angličtina |
Rok vydání: | 2010 |
Předmět: | |
Zdroj: | Acta stomatologica Croatica : International journal of oral sciences and dental medicine Volume 44 Issue 2 Web of Science |
ISSN: | 1846-0410 0001-7019 |
Popis: | Lichen planus je kronična imunosna upalna bolest koja često zahvaća sluznicu usne šupljine. Sustavne bolesti i lijekovi smatraju se precipitirajućim čimbenicima u njegovom nastanku. Svrha rada: ispitati prevalenciju sustavnih bolesti i lijekova u bolesnika s oralnim lihenom planusom(OLP) i utvrditi njihovu međusobnu povezanost. Materijal i metode: anamnestički podatci uzeti su retrospektivno iz medicinskih kartona 145 bolesnika s OLP-om od čega 104 žene i 41 muškarca koji su radi liječenja OLP-a upućeni na Zavod za oralnu medicinu. U svih je bolesnika dijagnoza OLPa postavljena na temelju kliničkih i histopatoloških kriterija. Podatci o sustavnim bolestima i lijekovima u bolesnika s OLP-om bilježeni su za period od dvije godine (jesen 2007.- jesen 2009.) i uspoređeni sa prevalencijom sustavnih bolesti i najčešće korištenih lijekova u bolesnika s oralnom leukoplakijom (LPL) kao i s podatcima opće populacije prema nacionalnom registru bolesti. Svi su podatci obrađeni primjenom χ2 testa, s razinom značajnosti od p Lichen planus is a chronic immunologic inflammatory disease that frequently involves oral mucosa. Systemic diseases and medications are considered to be precipitating factors in the development of oral lichen planus. Objective: The purpose of this study was to examine the prevalence of systemic diseases and medications in patients with oral lichen planus (OLP) and to determine possible causal relationship. Materials and methods: Retrospective data included medical records of 145 patients, 104 women and 41 men who were referred to the Department of Oral Medicine. All patients had clinical and histopathological criteria fulfilled for diagnosis of oral lichen planus. Data were collected for the period of two years (autumn 2007- autumn 2009). These data were compared with the prevalence of systemic diseases in patients with oral leukoplakia (LPL) and general Croatian population according to the national statistical register. The same comparison was made for the used medications. Obtained data were analyzed by use of χ2 test with level of significance p |
Databáze: | OpenAIRE |
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