Therapeutic effects of zinc supplementation in children with urinary tract infection
| Autor: | Yousefi, P., Moghaddasi, Z., Tabaei, A. |
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| Jazyk: | perština |
| Rok vydání: | 2011 |
| Předmět: | |
| Zdroj: | Majallah-i ̒Ilmī-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Simnān, Vol 12, Iss 02, Pp 204-208 (2011) Scopus-Elsevier |
| ISSN: | 1608-7046 |
| Popis: | Introduction: Urinary tract infection (UTI) is the most common disease of urinary tract. This disease lacks characteristic signs and symptoms and occasionally occurs with atypical presentations such as weight loss, anorexia, and growth failure. Zinc improves host immune-system response to many infections and has a significant role in immune system integrity. The aim of this was to study of zinc supplementation on treatment of UTI in children. Materials and Methods: In this clinical trial study, 200 children with UTI who were admitted to Amir Kabir hospital (Arak, Iran) were randomly divided into two control and case groups. Two groups were matched in age, gender, urine laboratory profiles, and clinical signs and symptoms such as fever, dysuria and frequency. The control group received only routine treatment of UTI. The case group, in addition to routine treatment of UTI, received oral zinc sulfate syrup. Results: Findings showed that dysuria and frequency in zinc-supplemented subjects recovered significantly sooner than control subjects, while the abdominal pain persisted longer. There were no significant differences in onset of fever remission and negative urine culture time 48h and 7-10 days after treatment between two groups. Conclusion: Zinc supplementation has a significant effect in ameliorating severe dysuria and frequency of urinary in UTI. When the abdominal pain is present, usage of this drug is not recommended. |
| Databáze: | OpenAIRE |
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