Delivery of a mucin domain enriched in cysteine residues strengthens the intestinal mucous barrier

Autor: Gouyer, Valérie, Dubuquoy, Laurent, Robbe-Masselot, Catherine, Neut, Christel, Singer, Elisabeth, Plet, Ségolène, Geboes, Karel, Desreumaux, Pierre, Gottrand, Frederic, Desseyn, Jean Luc
Přispěvatelé: Lille Inflammation Research International Center - U 995 (LIRIC), Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), Inserm, Université de Lille, CHU Lille, Lille Inflammation Research International Center - U 995 [LIRIC], Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Université de Lille, LillOA
Jazyk: angličtina
Rok vydání: 2015
Předmět:
[SDV] Life Sciences [q-bio]
[SDV]Life Sciences [q-bio]
Mesh:Animals
Mesh:Citrobacter rodentium/immunology
Mesh:Cysteine/chemistry
Mesh:Escherichia coli/immunology
Mesh:Gastrointestinal Microbiome/immunology
Mesh:Inflammatory Bowel Diseases/immunology
Mesh:Intestinal Mucosa/microbiology
Mesh:Intestines/microbiology
Mesh:Mice
Mesh:Inbred C57BL
Mesh:Mucin-2/genetics
Mesh:Mucin-2/metabolism
Mesh:Mucus/metabolism
Mesh:Epithelial Cells
Mesh:Mucin-6/metabolism
Mesh:Transgenic
Mesh:Goblet Cells
Mesh:Intestinal Mucosa/metabolism
Mesh:Protein Structure
Mesh:Tertiary
Mesh:Inflammatory Bowel Diseases/metabolism
Mesh:Tight Junctions/physiology
Mesh:Intestinal Mucosa/cytology
Mesh:Lactobacillus/isolation & purification
Mesh:Mucin-3/metabolism
Mesh:Microspheres
Mesh:Glycosylation
Mesh:Mucin-1/metabolism
MESH: Mesh:Glycosylation
MESH: Mesh:Microspheres
MESH: Mesh:Mucin-3/metabolism
MESH: Mesh:Lactobacillus/isolation & purification
ComputingMilieux_MISCELLANEOUS
MESH: Mesh:Mucin-1/metabolism
Zdroj: Scientific Reports
Scientific Reports, Nature Publishing Group, 2015, Scientific Reports, 5, ⟨10.1038/srep09577⟩
Scientific Reports, 2015, Scientific Reports, 5, ⟨10.1038/srep09577⟩
ISSN: 2045-2322
DOI: 10.1038/srep09577⟩
Popis: International audience
Databáze: OpenAIRE