Use of octaketide synthases to produce kermesic acid and flavokermesic acid
| Autor: | Birger Lindberg Møller, Bjørn Madsen, Dan Staerk, Okkels, F. T., Johan Andersen-Ranberg, Kenneth Thermann Kongstad, Binderup Kim, Bennedsen, M., Majse Nafisi, Paiman Khorsand-Jamal, Kannangara, R. M., Uffe Hasbro Mortensen, Ulf Thrane, Frandsen, Rasmus J. N. |
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| Zdroj: | Technical University of Denmark Orbit Aalborg University Møller, B L, Madsen, B, Stærk, D, Okkels, F T, Andersen-Ranberg, J, Kongstad, K T, Binderup, K, Bennedsen, M, Nafisi, M, Khorsand-Jamal, P, Kannangara, R M, Mortensen, U H, Thrane, U & Frandsen, R J N Dec. 15 2016, Use of octaketide synthases to produce kermesic acid and flavokermesic acid, Patent No. WO2016198564, IPC No. C12P 17/ 06 A I . |
| Popis: | A method for producing an octaketide derived aromatic compound of interest (e.g. carminic acid), wherein the method comprises (I): heterologous expression of a recombinantly introduced Type III polyketide synthase (PKS) gene encoding an octaketide synthase (OKS) to obtain non-reduced octaketide in vivo within the recombinant host cell and (II): converting in vivo the non-reduced octaketide of step (I) into a C14-C34 aromatic compound of interest (e.g. carminic acid). |
| Databáze: | OpenAIRE |
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