Self-perception of fracture risk: what can it tell us?
| Autor: | Litwic, AE, Compston, JE, Wyman, A, Siris, ES, Gehlbach, SH, Adachi, JD, Chapurlat, R, Díez-Pérez, A, LaCroix, AZ, Nieves, JW, Netelenbos, JC, Pfeilschifter, J, Rossini, M, Roux, C, Saag, KG, Silverman, S, Watts, NB, Greenspan, SL, March, L, Gregson, CL, Cooper, C, Dennison, EM, Global Longitudinal Study of Osteoporosis in Women (GLOW) Investigators |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Aging
Fracture risk Clinical Sciences Biomedical Engineering Comorbidity Risk Assessment Global Longitudinal Study of Osteoporosis in Women (GLOW) Investigators Medication Adherence Endocrinology & Metabolism Surveys and Questionnaires Humans Aged Practice Bone Density Conservation Agents Incidence Health Knowledge Middle Aged Self Concept Drug Utilization Treatment Adherence Attitudes Public Health and Health Services Osteoporosis Postmenopausal Female Osteoporotic Fractures Follow-Up Studies FRAX |
| Zdroj: | Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, vol 28, iss 12 |
| Popis: | In this study, we report that self-perception of fracture risk captures some aspect of fracture risk not currently measured using conventional fracture prediction tools and is associated with improved medication uptake. It suggests that adequate appreciation of fracture risk may be beneficial and lead to greater healthcare engagement and treatment.IntroductionThis study aimed to assess how well self-perception of fracture risk, and fracture risk as estimated by the fracture prediction tool FRAX, related to fracture incidence and uptake and persistence of anti-osteoporosis medication among women participating in the Global Longitudinal study of Osteoporosis in Women (GLOW).MethodsGLOW is an international cohort study involving 723 physician practices across 10 countries in Europe, North America and Australia. Aged ≥ 55years, 60,393 women completed baseline questionnaires detailing medical history, including co-morbidities, fractures and self-perceived fracture risk (SPR). Annual follow-up included self-reported incident fractures and anti-osteoporosis medication (AOM) use. We calculated FRAX risk without bone mineral density measurement.ResultsOf the 39,241 women with at least 1year of follow-up data, 2132 (5.4%) sustained an incident major osteoporotic fracture over 5years of follow-up. Within each SPR category, risk of fracture increased as the FRAX categorisation of risk increased. In GLOW, only 11% of women with a lower baseline SPR were taking AOM at baseline, compared with 46% of women with a higher SPR. AOM use tended to increase in the years after a reported fracture. However, women with a lower SPR who were fractured still reported lower AOM rates than women with or without a fracture but had a higher SPR.ConclusionsThese results suggest that SPR captures some aspect of fracture risk not currently measured using conventional fracture prediction tools and is also associated with improved medication uptake. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|