Patient-Reported Defecation and Micturition Problems Among Adults Treated for Sacrococcygeal Teratoma During Childhood-The Need for New Surveillance Strategies

Autor: Kremer, Marijke E. B., Derikx, Joep P. M., van Baren, Robertine, Heij, Hugo A., Wijnen, Marc H. W. A., Wijnen, René M. H., van der Zee, David C., van Heurn, Ernest L. W. E.
Přispěvatelé: Pediatrics, Other Research, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam Reproduction & Development (AR&D), Paediatric Surgery
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Pediatric Blood & Cancer, 63(4), 690. Wiley-Liss Inc.
Kremer, M E B, Derikx, J P M, van Baren, R, Heij, H A, Wijnen, M H W A, Wijnen, R M H, van der Zee, D C & van Heurn, E 2016, ' Patient-Reported Defecation and Micturition Problems Among Adults Treated for Sacrococcygeal Teratoma During ChildhoodThe Need for New Surveillance Strategies ', Pediatric Blood and Cancer, vol. 63, no. 4, pp. 690-694 . https://doi.org/10.1002/pbc.25857
Pediatric Blood and Cancer, 63(4), 690-694. Wiley-Liss Inc.
Pediatric blood & cancer, 63(4), 690-694. Wiley
Pediatric blood & cancer, 63(4), 690-694. Wiley-Liss Inc.
ISSN: 1545-5009
DOI: 10.1002/pbc.25857
Popis: Background: To evaluate defecation and micturition complaints in adults treated for sacrococcygeal teratoma (SCT) during childhood and to identify risk factors for soiling, urinary incontinence, and constipation beyond childhood. Procedure: Records of patients aged ≥18 treated for SCT during infancy in the Netherlands were retrospectively reviewed. Frequency and severity of soiling, constipation, and urinary incontinence were evaluated using questionnaires designed in line with the Krickenbeck classification. Problems during childhood were compared to outcomes at adult age in part of the cohort. Associations between patient- and disease-related factors with complaints beyond childhood were analyzed with the chi-square test or Fisher's exact test, when appropriate. Results: Of 47 included patients (mean age 26.2 years, SD ±6.5), 49% reported at least one defecation or micturition complaint. Urinary incontinence was present in 30% and had a greater negative impact than soiling (24%). Ten patients (21%) reported constipation; five found this severely bothering. Three patients reported social restrictions due to defecation or micturition complaints (6.4%). While sex and tumor histology were not identified as risk factors, a tumor diameter of >10 cm and Altman type I or type II SCT were associated with constipation during adulthood. Conclusions: One-third of the patients treated for SCT during childhood reported urinary and defecation problems beyond childhood. In only a minority of cases, these led to social restrictions. A greater tumor diameter was associated with a higher risk of constipation during adulthood. Prolonged surveillance strategies are advised for all patients with SCT.
Databáze: OpenAIRE
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