International estimated fetal weight standards of the INTERGROWTH-21st Project
Autor: | Stirnemann, J, Villar, J, Salomon, LJ, Ohuma, E, Ruyan, P, Altman, DG, Nosten, F, Craik, R, Munim, S, Cheikh Ismail, L, Barros, FC, Lambert, A, Norris, S, Carvalho, M, Jaffer, YA, Noble, JA, Bertino, E, Gravett, MG, Purwar, M, Victora, CG, Uauy, R, Bhutta, Z, Kennedy, S, Papageorghiou, AT, International Fetal and Newborn Growth Consortium for the 21st C, Scientific Advisory Committee, Steering Committees, INTERGROWTH-21st, INTERBIO-21st, Executive Committee, In addition for INTERBIO 21st, Project Coordinating Unit, Data Analysis Group, Data Management Group, Ultrasound Group, In addition for INTERBIO-21st, Anthropometry Group, Laboratory Processing Group, Neonatal Group, Environmental Health Group, Neurodevelopment Group, Participating countries and local investigators |
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Rok vydání: | 2017 |
Předmět: |
Adult
Participating countries and local investigators Data Management Group Environmental Health Group Ultrasound Group Gestational Age Reproductive health and childbirth Low Birth Weight and Health of the Newborn Paediatrics and Reproductive Medicine Pregnancy Clinical Research Preterm Neurodevelopment Group Infant Mortality Steering Committees Data Analysis Group Humans Birth Weight Prenatal Femur Prospective Studies Conditions Affecting the Embryonic and Fetal Periods Obstetrics & Reproductive Medicine In addition for INTERBIO 21st Ultrasonography Executive Committee Pediatric ultrasound screening Prevention Laboratory Processing Group INTERGROWTH-21st INTERBIO-21st Perinatal Period - Conditions Originating in Perinatal Period Anthropometry Group Cross-Sectional Studies Fetal Weight Neonatal Group Female Project Coordinating Unit Scientific Advisory Committee Head International Fetal and Newborn Growth Consortium for the 21st Century fetal growth [In addition for INTERBIO-21st] |
Zdroj: | Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology, vol 49, iss 4 |
ISSN: | 0960-7692 1469-0705 |
Popis: | OBJECTIVE: Estimated fetal weight (EFW) and fetal biometry are complementary measures used to screen for fetal growth disturbances. Our aim was to provide international EFW standards to complement the INTERGROWTH-21st Fetal Growth Standards that are available for use worldwide. METHODS: Women with an accurate gestational-age assessment, who were enrolled in the prospective, international, multicenter, population-based Fetal Growth Longitudinal Study (FGLS) and INTERBIO-21st Fetal Study (FS), two components of the INTERGROWTH-21st Project, had ultrasound scans every 5 weeks from 9-14 weeks' until 40 weeks' gestation. At each visit, measurements of fetal head circumference (HC), biparietal diameter, occipitofrontal diameter, abdominal circumference (AC) and femur length (FL) were obtained blindly by dedicated research sonographers using standardized methods and identical ultrasound machines. Birth weight was measured within 12 h of delivery by dedicated research anthropometrists using standardized methods and identical electronic scales. Live babies without any congenital abnormality, who were born within 14 days of the last ultrasound scan, were selected for inclusion. As most births occurred at around 40 weeks' gestation, we constructed a bootstrap model selection and estimation procedure based on resampling of the complete dataset under an approximately uniform distribution of birth weight, thus enriching the sample size at extremes of fetal sizes, to achieve consistent estimates across the full range of fetal weight. We constructed reference centiles using second-degree fractional polynomial models. RESULTS: Of the overall population, 2404 babies were born within 14 days of the last ultrasound scan. Mean time between the last scan and birth was 7.7 (range, 0-14) days and was uniformly distributed. Birth weight was best estimated as a function of AC and HC (without FL) as log(EFW) = 5.084820 - 54.06633 × (AC/100)3 - 95.80076 × (AC/100)3 × log(AC/100) + 3.136370 × (HC/100), where EFW is in g and AC and HC are in cm. All other measures, gestational age, symphysis-fundus height, amniotic fluid indices and interactions between biometric measures and gestational age, were not retained in the selection process because they did not improve the prediction of EFW. Applying the formula to FGLS biometric data (n = 4231) enabled gestational age-specific EFW tables to be constructed. At term, the EFW centiles matched those of the INTERGROWTH-21st Newborn Size Standards but, at |
Databáze: | OpenAIRE |
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