Beta defensin-1 gene (DEFB1) polymorphisms are not associated with atopic dermatitis in children and adolescents from northeast Brazil (Recife, Pernambuco)

Autor:	Segat, Ludovica, Guimarães, Rafael L, Brandão, Lucas A. C, Rocha, Cintia R. C, Zanin, Valentina, Trevisiol, Chiara, de Lima Filho, José Luiz, Crovella, Sergio
Přispěvatelé:	Segat, Ludovica, Guimarães, Rafael L, Brandão, Lucas A. C, Rocha, Cintia R. C, Zanin, Valentina, Trevisiol, Chiara, de Lima Filho, José Luiz, Crovella, Sergio
Jazyk:	angličtina
Rok vydání:	2010
Předmět:	Male beta-Defensins Adolescent Brazil Child Child Preschool Dermatitis Atopic Female Gene Frequency Genetic Predisposition to Disease Haplotypes Humans Infant Polymorphism Single Nucleotide Risk Factors Risk Factor Dermatitis Single Nucleotide Atopic Haplotype Polymorphism Preschool Human
Popis:	Atopic dermatitis (AD) is a common inflammatory skin disease resulting from the interplay between environmental, immunological and genetic factors. In our study, we investigated the role of three single nucleotide polymorphisms (SNPs) at 5'-UTR of DEFB1 gene, encoding for the human beta defensin-1, on the susceptibility to develop AD in a group of Brazilian children and adolescents.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::2f8c059c5a074398f421aa884b2e3902 https://hdl.handle.net/11368/2894056 Zobrazit plný text záznamu