| Autor: |
Kovac, D., Petrovecki, M., Jasic, M., Dobi-Babic, R., Ivanis, N., Rubinic, M., Krizanac, S., Nives Jonjić, Rizzardi, C., Melato, M. |
| Přispěvatelé: |
Kovac, D, Petrovecki, M, Jasic, M, DOBI BABIC, R, Ivanis, N, Rubinic, M, Krizanac, S, Jonjic, N, Rizzardi, Clara, Melato, Mauro |
| Rok vydání: |
2002 |
| Předmět: |
|
| Zdroj: |
Scopus-Elsevier |
| Popis: |
Gastrointestinal stromal tumors (GIST) are rare neoplasms of unknown etiology and pathogenesis. Their clinical behavior is very unpredictable and a reliable prognostic factor is lacking. The aim of this study was to analyze some prognostic factors and estimate which one is the most reliable. Thirty-eight biopsy specimens of GIST were immunolabeled for PCNA, CD34, vimetin, NSE and actin. The greatest diameter, histological grading, mitotic count, DNA-index and S-phase were estimated for each case. All patients were followed-up for at least 24 months or to death. The data were analysed by univariate and multivariate statistical analysis using a computer program. The results showed that greatest diameter, tumor grade, mitotic count and PCNA-index are prognostic factors in univariate analysis. In multivariate analysis only the greatest diameter is a useful prognostic factor for planning further therapy. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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