Identification of Transcription Factor Binding Sites in Streptomyces coelicolor A3(2) by Phylogenetic Comparison
| Autor: | Touzain, Fabrice, Lavigne, Patricia, Debled-Rennesson, Isabelle, Aigle, Bertrand, Leblond, Pierre, Kucherov, Gregory |
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| Přispěvatelé: | Applying discrete algorithms to genomics (ADAGE), INRIA Lorraine, Institut National de Recherche en Informatique et en Automatique (Inria)-Institut National de Recherche en Informatique et en Automatique (Inria)-Laboratoire Lorrain de Recherche en Informatique et ses Applications (LORIA), Institut National de Recherche en Informatique et en Automatique (Inria)-Université Henri Poincaré - Nancy 1 (UHP)-Université Nancy 2-Institut National Polytechnique de Lorraine (INPL)-Centre National de la Recherche Scientifique (CNRS)-Université Henri Poincaré - Nancy 1 (UHP)-Université Nancy 2-Institut National Polytechnique de Lorraine (INPL)-Centre National de la Recherche Scientifique (CNRS), Loria, Publications |
| Jazyk: | angličtina |
| Rok vydání: | 2003 |
| Předmět: | |
| Zdroj: | European Conference for Computer Biology-ECCB'2003 European Conference for Computer Biology-ECCB'2003, 2003, Paris, France |
| Popis: | Poster. Colloque avec actes sans comité de lecture. internationale.; International audience; The goal of this work is to identify, through computer methods, nucleotide patterns involved in transcription mechanisms in the bacteria Streptomyces coelicolor. In a preceding work [1], we explored the hypothesis of over-representation of regulation motifs in intergenic regions between genes of opposite orientation. While we were able to find by this method binding sites reported in literature, the number of false positives was too high to surely isolate any new interesting candidate motif. To obtain more reliable data, we turned to the comparative approach among phylogenetically related bacteria. |
| Databáze: | OpenAIRE |
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