The autoimmune hypothesis of narcolepsy and its unexplored clinical features
| Autor: | Schinkelshoek, M.S. |
|---|---|
| Přispěvatelé: | Lammers, G.J., Koning, F., Fronczek, R., Verschuuren, J.J.G.M., Overeem, S., Kornum, B.R., Leiden University |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | None |
| Popis: | The mechanisms involved in the autoimmune hypothesis of narcolepsy are investigated in this thesis. The role of HLA, auto- and cross-reactive T cells is explored and immune cell populations of interest are identified by a new technique, called mass cytometry. The second part of the thesis assesses unexplored clinical features of narcolepsy, such as weight gain and sleep state misperception. |
| Databáze: | OpenAIRE |
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