Neurodevelopmental outcomes of preterm infants after randomisation to initial resuscitation with lower (FiO2<0.3) or higher (FiO2>0.6) initial oxygen levels. An individual patient meta-analysis
| Autor: | Oei, Ju Lee, Kapadia, Vishal, Rabi, Yacov, Saugstad, Ola Didrik, Rook, Denise, Vermeulen, Marijn J., Boronat, Nuria, Thamrin, Valerie, Tarnow-Mordi, William, Smyth, John, Wright, Ian M., Lui, Kei, van Goudoever, Johannes B., Gebski, Val, Vento, Maximo |
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| Přispěvatelé: | Neonatology, Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam Reproduction & Development (AR&D), Pediatrics, AGEM - Endocrinology, metabolism and nutrition, ACS - Diabetes & metabolism |
| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Archives of disease in childhood. Fetal and neonatal edition, 107(4), 386-392. BMJ Publishing Group Archives of Disease in Childhood-Fetal and Neonatal Edition, 107(4), 386-392. BMJ Publishing Group Archives of Disease in Childhood. Fetal and Neonatal Edition, 107(4), 386-392. BMJ Publishing Group |
| ISSN: | 1359-2998 |
| Popis: | OBJECTIVE: To determine the effects of lower (≤0.3) versus higher (≥0.6) initial fractional inspired oxygen (FiO2) for resuscitation on death and/or neurodevelopmental impairment (NDI) in infants 80% was associated with decreased disability/death (14%, 7% to 21%) and cognitive scores >85 (10%, 3% to 18%, p=0.01). Multinomial regression analysis noted decreased death with 5-minute SpO2 ≥80% (odds (95% CI) 09.62, 0.98 to 0.96) and gestation (0.52, 0.41 to 0.65), relative to children without death or NDI. CONCLUSION: Initial FiO2 was not associated with difference in risk of disability/death at 2 years in infants |
| Databáze: | OpenAIRE |
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