General characteristics and prognostic factors of pneumonia cases developed during pandemic (h1n1) influenza-a virus ınfection in Turkey

Autor: TEVFİK ÖZLÜ, YILMAZ BÜLBÜL, MEHMET SEZAİ TAŞBAKAN, Hatice KILIÇ, Tülin KUYUCU, TEKİN YILDIZ, Tarkan ÖZDEMİR, Serap DURU, FUNDA ÖZTUNA, NALAN ADIGÜZEL, LEYLA SAĞLAM, Ayşın COŞKUN ŞAKAR, Tacettin ÖRNEK, Gazi GÜNDÜZ, Ayten FİLİZ, Levent ÖZDEMİR, NİGAR GÜLFER OKUMUŞ
Přispěvatelé: KARADENİZ TEKNİK ÜNİVERSİTESİ, EGE ÜNİVERSİTESİ, ANKARA ATATÜRK EĞİTİM VE ARAŞTIRMA HASTANESİ > ANKARA ATATÜRK EĞİTİM VE ARAŞTIRMA HASTANESİ, GÖĞÜS HASTALIKLARI, Tanımlanmamış Kurum, DİCLE ÜNİVERSİTESİ, ANKARA DIŞKAPI YILDIRIM BEYAZIT EĞİTİM VE ARAŞTIRMA HASTANESİ > ANKARA DIŞKAPI YILDIRIM BEYAZIT EĞİTİM VE ARAŞTIRMA HASTANESİ, GÖĞÜS HASTALIKLARI, ATATÜRK ÜNİVERSİTESİ, CELÂL BAYAR ÜNİVERSİTESİ, GAZİANTEP ÜNİVERSİTESİ, İSTANBUL ÜNİVERSİTESİ
Jazyk: angličtina
Rok vydání: 2013
Popis: Objective: Unlike seasonal influenza, seen in previous years, the strain identified in the 2009 influenza-A pandemic involved high mortality. In this study, prognostic factors and general characteristics of pneumonia cases developed in Turkey during the H1N 1 pandemic between October 2009 and January 2010 were analyzed. Study Design: Multicenter retrospective study. Material and Methods: This multicentric retrospective study was conducted between August and October 2010 and patients data were collected by means of standard forms. Results: The study included 264 pneumonia cases, collected from 14 different centers. Mean age was 47.5±18.6 years. Nineteen patients (7.2%) were preg- nant or had a new birth and comorbid diseases were detected in 52.3% of all patients. On admission, 35 (13.8%) cases had altered mental status. Overall, 32.6% were treated in intensive care units (ICU) and invasive/non-invasive mechanical ventilation was performed in 29.7%. The mean duration of ICU stay was 2.9±6.2 and total hospital stay was 12.0±9.4 days. Mortality rate was 16.8% (43-cases). The length of ICU treatment, total hospital stay, and mortality were significantly higher in H1N1-confirmed patients. Mortality was significantly higher in patients with dyspnea, cyanosis, and those who had altered mental status on admission. Patients who died had significantly higher rate of peripheral blood neutrophils, lower platelet counts, higher BUN, and lower SaO2 levels. Conclusion: This study showed that pneumonia developed during H1N1 pandemic in our country had resulted in a high mortality. Mortality was espe- cially high among patients with cyanosis, altered mental state and those with lower SaO2.
Databáze: OpenAIRE