Differential effect of valproate and its Delta(2)- and Delta(4)-unsaturated metabolites, on the beta-oxidation rate of long-chain and medium-chain fatty acids
Autor: | Silva, MFB, Ruiter, JPN, IJlst, L, Jakobs, C, Duran, M, de Almeida, IT, Wanders, RJA |
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Přispěvatelé: | Repositório da Universidade de Lisboa |
Jazyk: | angličtina |
Rok vydání: | 2001 |
Předmět: | |
Zdroj: | Repositório Científico de Acesso Aberto de Portugal Repositório Científico de Acesso Aberto de Portugal (RCAAP) instacron:RCAAP |
Popis: | Overall fatty acid oxidation rates were investigated in rat hepatocytes using [9,10-H-3]palmitic, [9,10-H-3]-oleic, [9.10-H-3]-myristic and [2,3-H-3]-phenylpropionic acids. The effect of both valproate (VPA) (0-10 mM) and two of its unsaturated metabolite |
Databáze: | OpenAIRE |
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