A review on the key factors that control muscle development and growth in gilthead sea bream
| Autor: | Vélez, Emilio, Azizi, Sheida, Perelló-Amorós, Miguel, Lutfi, Esmail, Sánchez-Moya, Albert, Pérez-Sánchez, Jaume, Calduch-Giner, Josep A., Navarro, Isabel, Fernández-Borràs, Jaume, Blasco, Josefina, Capilla, E., Gutiérrez, Joaquím |
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| Přispěvatelé: | Calduch-Giner, Josep A. [0000-0003-3124-5986], Ministerio de Economía y Competitividad (España), Generalitat de Catalunya, Calduch-Giner, Josep A. |
| Rok vydání: | 2017 |
| Zdroj: | Digital.CSIC. Repositorio Institucional del CSIC instname |
| Popis: | Trabajo presentado en el 11º Congreso de la Asociación Ibérica de Endocrinología Comparada (AIEC), celebrado en Vigo (España), del 13 al 15 de julio de 2017 Unlike mammals, many fish species are indeterminate growers. Muscle growth involves hypertrophy and hyperplasia that continue during the whole life of the fish, processes that can be modulated by different factors. Growth hormone (GH)/insulinlike growth factors (IGFs) endocrine axis is the main intrinsic factor. Diet composition and physical activity are important external regulators not only of the fish somatic growth but also of muscle characteristics. Over the last years, we have been investigating in gilthead sea bream (Sparus aurata) the possibility to increase growth with different approaches: injection of recombinant bovine GH (rBGH), moderated and sustained swimming activity or diet supplementation. We have determined biometrical parameters, hormones levels, gene and protein expression of growth, myogenesis, proteolysis or osteogenesis gene markers in white muscle, liver or bone, and also analyzed muscle histology. In the different models we have found that an increase in body weight up to 30% can be obtained, and the ratio of circulating GH/IGF-I has appeared as a very good indicator of the growing condition. Moreover, the effects of these factors on the expression of GH and IGF-I receptors, binding proteins and specific regulators in the different tissues will be discussed as have helped to understand how this complex scenario can determine the enhancement of growth and quality of the fish; thus, contributing to the improvement of aquaculture production. Acknowledgements: to Elanco Animal Health for kindly providing the rBGH. Supported by MINECO (AGL2012-39768, AGL2014-57974-R and AGL2015- 70679-R) and Catalonian Government (2014SGR-01371 and XRAq). |
| Databáze: | OpenAIRE |
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