Relating mulltidrug resistance phenotypes in the kinetic properties of their drug efflux pumps
Autor: | Westerhoff, H.V., Riethorst, A., Jongsma, A.P.M. |
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Přispěvatelé: | Molecular Cell Physiology |
Jazyk: | angličtina |
Rok vydání: | 2000 |
Předmět: | |
Zdroj: | European Journal of Biochemistry, 267, 5355-5368. Wiley-Blackwell Westerhoff, H V, Riethorst, A & Jongsma, A P M 2000, ' Relating mulltidrug resistance phenotypes in the kinetic properties of their drug efflux pumps. ', European Journal of Biochemistry, vol. 267, pp. 5355-5368 . https://doi.org/10.1046/j.1432-1327.2000.01559.x |
ISSN: | 0014-2956 |
DOI: | 10.1046/j.1432-1327.2000.01559.x |
Popis: | The simplest model for pump-mediated multidrug resistance is elaborated quantitatively. The way in which toxicity data should be evaluated to characterize most effectively the drug-efflux pump is then examined. The isotoxic drug dose (D |
Databáze: | OpenAIRE |
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