Relating mulltidrug resistance phenotypes in the kinetic properties of their drug efflux pumps

Autor: Westerhoff, H.V., Riethorst, A., Jongsma, A.P.M.
Přispěvatelé: Molecular Cell Physiology
Jazyk: angličtina
Rok vydání: 2000
Předmět:
Zdroj: European Journal of Biochemistry, 267, 5355-5368. Wiley-Blackwell
Westerhoff, H V, Riethorst, A & Jongsma, A P M 2000, ' Relating mulltidrug resistance phenotypes in the kinetic properties of their drug efflux pumps. ', European Journal of Biochemistry, vol. 267, pp. 5355-5368 . https://doi.org/10.1046/j.1432-1327.2000.01559.x
ISSN: 0014-2956
DOI: 10.1046/j.1432-1327.2000.01559.x
Popis: The simplest model for pump-mediated multidrug resistance is elaborated quantitatively. The way in which toxicity data should be evaluated to characterize most effectively the drug-efflux pump is then examined. The isotoxic drug dose (D
Databáze: OpenAIRE