Sastavnice metaboličkog sindroma kao nezavisni čimbenici rizika u bolesnika s akutnim koronarnim sindromom
| Autor: | Kranjčec, Darko |
|---|---|
| Přispěvatelé: | Vincelj, Josip, dostupno, nije |
| Jazyk: | chorvatština |
| Rok vydání: | 2015 |
| Předmět: | |
| Popis: | Metabolički sindrom (MetS) je prema SZO istovremena prisutnost dijabetes melitusa/intolerancije glukoze te najmanje dviju od slijedećih sastavnica: arterijske hipertenzije, centralne pretilosti, dislipidemiji i/ili mikoralbuminurije. Cilj istraživanja bio je utvrditi učestalost MetS i njegovih sastavnica kod bolesnika s akutnim koronarnim sindromom. Nadalje htjela se usporediti težina akutnog infarkta miokarda mjerena vršnim vrijednostima CK i MB-CK kod bolesnika sa i bez MetS te usporediti težinu infarkta miokarda u muškaraca i žena sa i bez MetS. Analiziran je i utjecaj pojedinih sastavnica MetS na težinu infarkta miokarda i srčano popuštanje. U istraživanje je uključeno 230 bolesnika s akutnim koronarnim sindromom hospitaliziranih u koronarnoj jednici KB Dubrava od siječnja 2006. do lipnja 2007. godine. Bolesnici zaprimljeni u subakutnoj fazi infarkta miokarda te oni koji nisu dali pristanak nisu uključeni u istraživanje. Glede statističke obrade kontinuirane varijable su prikazane kao srednja (M) i standarna devijacija (SD). Dihotomne varijable su prikazane kao postotak. Studentov t test je upotrijebljen za komparaciju kontinuiranih varijabli, dok je Fischerov Exact Test uzet za komparaciju dihotomnih varijabli. Vrijednost p Metabolic syndrome (MetS) is occurrence of diabetes mellitus/glucose intolerance and at least two of the following: arterial hypertension, central obesity, dyslipidemia and/or microalbuminuria in the same patient (definition by WHO). Aim of the study was to find out what is the occurrence of MetS and its components in patients with acute coronary syndrome. Furthermore, we compared size of myocardial infarction expressed in “peak-CK” and “peak-MB-CK” values as a “surrogate” for myocardial infarction size in patients with and without MetS. We also analyzed myocardial infarction size according to gender in groups with and without MetS. Then we analyzed influence of particular components of MetS on myocardial infarction size and heart failure. 230 patients with acute coronary syndrome admitted at coronary care unit of University hospital Dubrava between January 2006. and June 2007. were analysed. Patients admitted in subacute phase of myocardial infarction or those that did not give consent were not included in trial. Continuous variables were expressed as mean (M) and standard deviation (SD). Dichotomous variables were expressed as percentage. Student's t test was used to compare continuous variables, and Fisher's Exact Test was used to compare dichotomous variables. A p value |
| Databáze: | OpenAIRE |
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