Stereoselective synthesis of highly substituted tetrahydrofurans by diverted carbene O–H insertion reaction
| Autor: | Nicolle, Simon M., Lewis, William, Hayes, Christopher J., Moody, Christopher J. |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| ISSN: | 1433-7851 1521-3773 |
| Popis: | Copper or rhodium catalyzed reaction of diazocarbonyl compounds with β-hydroxyketones gives highly substituted tetrahydrofurans with excellent diastereoselectivity, under mild conditions, in a single step process that starts as a carbene O–H insertion reaction but is diverted by an intramolecular aldol reaction. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text