Multiple myeloma associated with a secondary amyloidosis. Report of one case

Autor:	Rodríguez-Lagos FA, Sorlí JV, Calviño-Naveira MC, Capell NE
Rok vydání:	2018
Předmět:	Plasma Cells Congo Red Amyloidosis Multiple Myeloma
Zdroj:	REVISTA MEDICA DE CHILE r-FISABIO. Repositorio Institucional de Producción Científica instname r-FISABIO: Repositorio Institucional de Producción Científica Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
ISSN:	0034-9887
Popis:	Multiple Myeloma is a myeloproliferative disorder of plasma cells, which may be complicated with secondary amyloidosis. We report a 48 year old woman consulting to primary care for weight loss and malaise. An initial laboratory study revealed a hypogammaglobulinemia with a monoclonal component and lambda light chains. These results motivated her derivation to hematology: her serum calcium was 11.8 mg/dl, immunofluorescence showed a monoclonal component of lambda chains and urine Bence-Jones protein was positive. A bone marrow biopsy confirmed plasma cell infiltration. A Congo-red stain of a rectal biopsy was positive. The patient was treated with thalidomide, bortezomid and dexamethasone.
Databáze:	OpenAIRE
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