Greater Levels of Self-Reported Adherence to Pre-Exposure Prophylaxis (PrEP) are Associated with Increased Condomless Sex Among Men Who Have Sex with Men
| Autor: | Pasipanodya, Elizabeth C, Li, Michael J, Jain, Sonia, Sun, Xiaoying, Tobin, Jessica, Ellorin, Eric, Dube, Michael, Daar, Eric S, Corado, Katya, Milam, Joel, Blumenthal, Jill, Morris, Sheldon H, Moore, David J, and the California Collaborative Treatment Group (CCTG) |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Male
Adult Social Work Condomless sex genetic structures Anti-HIV Agents Sexual Behavior HIV Infections Sexual and Gender Minorities (SGM/LGBT*) Medication Adherence Condoms Young Adult Sexual and Gender Minorities Behavioral and Social Science Humans and the California Collaborative Treatment Group Unsafe Sex Prevention HIV Homosexuality PrEP Risk compensation Good Health and Well Being Infectious Diseases Adherence Public Health and Health Services HIV/AIDS Pre-Exposure Prophylaxis Self Report Public Health Infection |
| Zdroj: | AIDS and behavior, vol 24, iss 11 |
| Popis: | The effectiveness of pre-exposure prophylaxis (PrEP) against HIV acquisition depends on treatment adherence; however, within-person associations between levels of PrEP adherence and engagement in condomless sex have not been well studied. In the context of a demonstration project, 372 men who have sex with men received once-daily PrEP and completed six study visits over 48weeks. Two-part growth mixture modeling was used to examine the longitudinal trajectory of condomless anal intercourse (CAI) and self-reports of PrEP adherence, controlling for relevant covariates. Over time, greater PrEP adherence was contemporaneously associated with both a higher likelihood of engaging in any CAI and with a greater number of CAI acts. Substance use was also associated with a higher likelihood of engaging in CAI. Contemporaneous associations between self-reported PrEP adherence and CAI suggest that adherence behaviors may be motivated by the desire to mitigate risk of HIV infection; however, exact directionality is unknown. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|