Institute of Tropical Medicine, Nagasaki University

Autor: Kheong, Chew Tong, Balasubramaniam, Vijayamalar, Sinniah, Mangalam, Igarashi, Akira
Jazyk: angličtina
Rok vydání: 1993
Zdroj: 熱帯医学 Tropical medicine. 35(2):65-73
ISSN: 0385-5643
Popis: Sera from clinical dengue cases in Malaysia were examined to detect IgG- as well as IgM-class anti-dengue antibodies by the indirect ELISA with or without treatment by 3 kinds of IgG-adsorbents. Relative adsorption factor (AF) as determined by the decreased ELISA-OD ratio was 0.42-0.58 for IgG and 0.33-0.39 for IgM, respectively. After IgG-adsorbents treatment, however, the number of anti-dengue IgM-positive serum specimen decreased from 11-20% of the untreated control. The result indicated that pretreatment of test sera with IgG-adsorbents did not improve or even reduced the sensitivity to detect anti-dengue IgM antibodies in the test sera.
熱帯医学 Tropical medicine 35(2). p65-73, 1993
Databáze: OpenAIRE