Calcium Channels in Vascular Smooth Muscle

Autor:	Ghosh, D, Syed, AU, Prada, MP, Nystoriak, MA, Santana, LF, Nieves-Cintrón, M, Navedo, MF
Rok vydání:	2017
Předmět:	Biochemistry & Molecular Biology Contraction Sarcoplasmic reticulum Arteries Pharmacology and Pharmaceutical Sciences Ca(2+) signaling Myogenic tone Vascular Ion channels Muscle Animals Humans Calcium Smooth Calcium Channels Calcium Signaling
Zdroj:	Ghosh, D; Syed, AU; Prada, MP; Nystoriak, MA; Santana, LF; Nieves-Cintrón, M; et al.(2017). Calcium Channels in Vascular Smooth Muscle. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/2mx0c74r
Popis:	© 2017 Elsevier Inc. Calcium (Ca2+) plays a central role in excitation, contraction, transcription, and proliferation of vascular smooth muscle cells (VSMs). Precise regulation of intracellular Ca2 + concentration ([Ca2 +]i) is crucial for proper physiological VSM function. Studies over the last several decades have revealed that VSMs express a variety of Ca2 +-permeable channels that orchestrate a dynamic, yet finely tuned regulation of [Ca2 +]i. In this review, we discuss the major Ca2 +-permeable channels expressed in VSM and their contribution to vascular physiology and pathology.
Databáze:	OpenAIRE
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