Web tools for the prioritization of candidate disease genes

Autor:	Oti, M.O., Ballouz, S., Wouters, M.A.
Rok vydání:	2011
Předmět:	Energy and redox metabolism Mitochondrial medicine [NCMLS 4]
Zdroj:	Methods in Molecular Biology, 760, 189-206 Methods in Molecular Biology, 760, pp. 189-206
ISSN:	1064-3745
Popis:	Item does not contain fulltext Despite increasing sequencing capacity, genetic disease investigation still frequently results in the identification of loci containing multiple candidate disease genes that need to be tested for involvement in the disease. This process can be expedited by prioritizing the candidates prior to testing. Over the last decade, a large number of computational methods and tools have been developed to assist the clinical geneticist in prioritizing candidate disease genes. In this chapter, we give an overview of computational tools that can be used for this purpose, all of which are freely available over the web.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::2289014f64c04852a1f3ec1c7f85e166 http://hdl.handle.net/2066/97510 Zobrazit plný text záznamu