NIDA's Clinical Trials Network: an opportunity for HIV research in community substance abuse treatment programs

Autor: Tross, Susan, Campbell, Aimee NC, Calsyn, Donald A, Metsch, Lisa R, Sorensen, James L, Shoptaw, Steven, Haynes, Louise, Woody, George E, Malow, Robert M, Brown, Lawrence S, Feaster, Daniel J, Booth, Robert E, Mandler, Raul N, Masson, Carmen, Holmes, Beverly W, Colfax, Grant, Brooks, Audrey J, Hien, Denise A, Schackman, Bruce R, Korthuis, P Todd, Miele, Gloria M, Clinical Trials Network HIV Special Interest Group
Rok vydání: 2011
Předmět:
Zdroj: The American journal of drug and alcohol abuse, vol 37, iss 5
Popis: Background/objectivesHIV continues to be a significant problem among substance users and their sexual partners in the United States. The National Drug Abuse Treatment Clinical Trials Network (CTN) offers a national platform for effectiveness trials of HIV interventions in community substance abuse treatment programs. This article presents the HIV activities of the CTN during its first 10 years.ResultsWhile emphasizing CTN HIV protocols, this article reviews the (1) HIV context for this work; (2) the collaborative process among providers, researchers, and National Institute on Drug Abuse CTN staff, on which CTN HIV work was based; (3) results of CTN HIV protocols and HIV secondary analyses in CTN non-HIV protocols; and (4) implications for future HIV intervention effectiveness research in community substance abuse treatment programs.Conclusion/significanceWhile the feasibility of engaging frontline providers in this research is highlighted, the limitations of small to medium effect sizes and weak adoption and sustainability in everyday practice are also discussed.
Databáze: OpenAIRE