Genetic characterisation of the ethambutol resistance-determining region in Mycobacterium tuberculosis

Autor:	Perdigao, Joao, Macedo, Rita, Ribeiro, Ana, Brum, Laura, Portugal, Isabel
Přispěvatelé:	Repositório da Universidade de Lisboa
Jazyk:	angličtina
Rok vydání:	2009
Předmět:	Infectious Diseases Pharmacology & Pharmacy Microbiology
Zdroj:	Repositório Científico de Acesso Aberto de Portugal Repositório Científico de Acesso Aberto de Portugal (RCAAP) instacron:RCAAP
Popis:	Ethambutol (EMB) is a first-line antitubercular drug that inhibits arabinogalactan and lipoarabinomannan biosynthesis. Resistance to EMB has traditionally been associated with embB mutations, especially in the Met306 codon. In this study, the region encom. - Fundacao Calouste Gulbenkian, Lisbon, Portugal [FCG 001013]. - Funding: This work was supported by Fundacao Calouste Gulbenkian, Lisbon, Portugal (grant FCG 001013).
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::2168c518036cbca1af8e6db58a2e9a29 https://hdl.handle.net/10451/21542 Zobrazit plný text záznamu