Serendipity in detecting disease in low prostate-specific antigen ranges

Autor: Vis, A. N., Kranse, R., Roobol, M., Van Der Kwast, Th H., Schröder, F. H.
Přispěvatelé: Urology, CCA - Imaging and biomarkers
Jazyk: angličtina
Rok vydání: 2002
Předmět:
Zdroj: BJU International, 89(4), 384-389. Wiley-Blackwell
Vis, A N, Kranse, R, Roobol, M, Van Der Kwast, T H & Schröder, F H 2002, ' Serendipity in detecting disease in low prostate-specific antigen ranges ', BJU International, vol. 89, no. 4, pp. 384-389 . https://doi.org/10.1046/j.1464-4096.2001.01868.x
ISSN: 1464-4096
DOI: 10.1046/j.1464-4096.2001.01868.x
Popis: Objective: To assess the magnitude of prostate cancer detection by serendipity (the coincidental detection of prostate cancer during the evaluation of an abnormal screening test result) when a digital rectal examination (DRE) and transrectal ultrasonography (TRUS) are used as initial screening tests for prostate cancer in men with low levels of prostate-specific antigen (PSA; 0.0-3.9 ng/mL). Patients and methods: In all, 117 participants of a population-based screening study were diagnosed with prostate cancer after a standard evaluation of an abnormal screening test result; 49 underwent radical prostatectomy. Serendipity was defined as either: (i) the presence of prostate cancer opposite to the side that raised suspicion for cancer on DRE and/or TRUS; (ii) a negative lesion-directed biopsy while cancer was present in one or more of the cores of the sextant biopsy; (iii) a tumour volume of
Databáze: OpenAIRE
Externí odkaz: