Bone turnover, joint damage and bone mineral density in early rheumatoid arthritis treated with combination therapy including high-dose prednisolone
| Autor: | Verhoeven, A.C., Boers, M., Koppele, J.M. te, Laan, W.H. van der, Markusse, H.M.Geusens, P., Linden, S. van der |
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| Přispěvatelé: | Gaubius Instituut |
| Jazyk: | angličtina |
| Rok vydání: | 2001 |
| Předmět: |
Adult
Male Health Biology Biomedical Research Collagen crosslinks Prednisolone Anti-Inflammatory Agents Outcomes Early rheumatoid arthritis Arthritis Rheumatoid Bone Density Bone mineral density Humans Amino Acids Glucocorticoids Aged Deoxypyridinoline Anti-Inflammatory Agents Non-Steroidal Middle Aged Postmenopause Sulfasalazine Cross-Linking Reagents Methotrexate Antirheumatic Agents Regression Analysis Drug Therapy Combination Female Joints Bone Remodeling Collagen Pyridinoline |
| Zdroj: | Rheumatology, 11, 40, 1231-1237 |
| Popis: | Objectives. Exploration of bone metabolism changes at different levels of disease activity, both with and without oral corticosteroid therapy, and prediction of changes in joint damage and bone density from the observed changes in markers of bone turnover. Methods. Data analysis from a randomized clinical trial with 155 rheumatoid arthritis (RA) patients; median age 50 yr, early and active disease (diagnosis |
| Databáze: | OpenAIRE |
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