Radiotratamiento de mafenida10 % Crema
Autor: | Marta Guerra Ordóñez, Enrique Prieto Miranda, José Carlos Melo, Zoraima Pomares |
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Jazyk: | Spanish; Castilian |
Rok vydání: | 1996 |
Předmět: | |
Zdroj: | Revista Cubana de Farmacia, Vol 30, Iss 2, p 0 (1996) Revista Cubana de Farmacia, Vol 30, Iss 2 |
ISSN: | 1561-2988 0034-7515 |
Popis: | The application of ioninzing radiations with decontaminant ends is an alternative to guarantee the microbiological quality of many pharmaceuticals. The radiotreatment with mafenide 10 % cream, which did not meet the microbiological quality specifications established in the country, was carried out. The microbial charge was determined and a dosage study of the product was conducted, evaluating 3, 5, 7, and 10 KGy of gamma radiations with a Co60 radioisotopic source. Microbiological and chemicophysical evaluations were carried out before and after the treatment. It was decided to irradiate the product with 3 KGy as a minimum dose, in a continual way and in the "Product I" plant of the Food Industry Research Institute. |
Databáze: | OpenAIRE |
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