Radiotratamiento de mafenida10 % Crema

Autor: Marta Guerra Ordóñez, Enrique Prieto Miranda, José Carlos Melo, Zoraima Pomares
Jazyk: Spanish; Castilian
Rok vydání: 1996
Předmět:
Zdroj: Revista Cubana de Farmacia, Vol 30, Iss 2, p 0 (1996)
Revista Cubana de Farmacia, Vol 30, Iss 2
ISSN: 1561-2988
0034-7515
Popis: The application of ioninzing radiations with decontaminant ends is an alternative to guarantee the microbiological quality of many pharmaceuticals. The radiotreatment with mafenide 10 % cream, which did not meet the microbiological quality specifications established in the country, was carried out. The microbial charge was determined and a dosage study of the product was conducted, evaluating 3, 5, 7, and 10 KGy of gamma radiations with a Co60 radioisotopic source. Microbiological and chemicophysical evaluations were carried out before and after the treatment. It was decided to irradiate the product with 3 KGy as a minimum dose, in a continual way and in the "Product I" plant of the Food Industry Research Institute.
Databáze: OpenAIRE