| Autor: |
Okada, Kenji, Wada, Seishi, Kajihara, Hiroki, Sueda, Taijiro, Matsuura, Yuichiro |
| Jazyk: |
angličtina |
| Rok vydání: |
1997 |
| Předmět: |
|
| Zdroj: |
Hiroshima Journal of Medical Sciences. 46(4):115-123 |
| Popis: |
The aim of this study was to assess the effectiveness of Perfluorotributylamine/Pluronic F-68 Stem-Emulsion (FC43se) against hyperacute rejection in rabbit-pig xenodiscordant transplantation in an ex-vivo lung model. Rabbits were divided into two groups. In Group 1 (control), after extraction, the lungs were connected directly to the experimental circuit as soon as possible. The lungs were then perfused with 100 ml of pig blood only. In Group 2 (FC(+) Group), after extraction, the lungs were connected to the same circuit as soon as possible. The lungs were then perfused with 10 ml of FC43se plus 90 ml of pig blood. The duration of perfusion was defined from when the perfusion started until the PAP reached 50 mmHg. Significant differences in survival were seen between Group 1 and Group 2: in Group 1, the survival time was 51.9±16.8 min, whereas in Group 2 the survival time was 76.9±12.4 min (p |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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