3D skin microfluidic phantom for in vitro wearable testing

Autor: Rabost Garcia, Genís, Carreras Gallo, Óscar, Colmena, Valeria, Aguilar, Javier, Punter Villagrasa, Jaime, Muñoz Pascual, Francesc Xavier, Farré Lladós, Josep|||0000-0001-5909-0176, Casals Terré, Jasmina|||0000-0002-1368-3950
Přispěvatelé: Universitat Politècnica de Catalunya. Doctorat en Enginyeria Mecànica, Fluids i Aeronàutica, Universitat Politècnica de Catalunya. Departament d'Enginyeria Mecànica, Universitat Politècnica de Catalunya. MICROTECH LAB - Microtechnology for the Industry
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: UPCommons. Portal del coneixement obert de la UPC
Universitat Politècnica de Catalunya (UPC)
Popis: A standardized and cost-effective perspiration phantom for in vitro testing is needed to replace the variable and resource consuming human tests at research level. Here, an alternative to the existing devices, which mainly are made of laser-perforated thin membranes, is presented using polydimethylsiloxane (PDMS) and soft lithography. The proposed method overcomes the fabrication challenges of replicating the eccrine sweat gland structure. Sweat glands conduits are faithfully defined in-plane and the skin interface is created by bonding multiple PDMS layers. Parameters such as sweat duct diameter, sweat gland density and wettability properties were successfully replicated
Databáze: OpenAIRE