Effectiveness of Systemic Therapies in Patients with Obesity and Psoriasis: A Single-center Retrospective Study
| Autor: | Bonifati, C., Capoccia, R., Dario Graceffa, Morrone, A. |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | Acta Dermatovenerologica Croatica Volume 29 Issue 2 Scopus-Elsevier |
| ISSN: | 1847-6538 1330-027X |
| Popis: | This retrospective study included 63 patients with obesity (Body Mass Index; BMI ≥ 30) and psoriasis. Our aim was to verify the effectiveness of different systemic therapies administered to the above cohort of subjects over a period of 1 year. Improvements of 75%, 90%. and 100% compared with the baseline Psoriasis Area Severity Index (PASI 75, PASI 90, and PASI 100, respectively) were used as clinical outcome measures. In a median time of 16 weeks, 85.7%, 68.2%, and 38.0% of patients achieved PASI 75, PASI 90, and PASI 100, respectively. In parallel, the Dermatology Life Quality Index (DLQI) and the visual analog score for measuring itch intensity (VAS itch) decreased significantly (P31.7 and the presence of psoriatic arthritis were negative predictors for the achievement of PASI 90, while having a DLQI >6 was a positive predictor |
| Databáze: | OpenAIRE |
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