Clostridium difficile Toxin in Adult Inpatients in an Urban Hospital in Malawi: Associations with HIV Status, CD4 Count and Diarrhoea

Autor: Beadsworth, M. B. J., Keeley, A. J., Roberts, P., Farragher, B., Watson, A., Nicholas Beeching
Předmět:
Zdroj: Liverpool School of Tropical Medicine
Scopus-Elsevier
Popis: Clostridium difficile Infection (CDI) is the cause of substantial morbidity and mortality in the developed world. However, very little is known about the burden of CDI in sub-Saharan Africa where less antibiotic restriction, high HIV prevalence and greater impact from nosocomial infection mean the potential for a significant disease burden is great. Researchers investigated the prevalence of Clostridium difficile Toxin (CDT), assessing association with HIV, CD4 count and diarrhoea in medical in-patients in Malawi. In 206 patients tested for CDT, 28 (13.6%) were positive. No significant associations were seen with either diarrhoea or HIV. There was a non-statistically significant (p = 0.056) association between CD4 counts of
Databáze: OpenAIRE