Anti-Markovnikov Hydrofunctionalization of Alkenes: Use of a Benzyl Group as a Traceless Redox-Active Hydrogen Donor

Autor: Lonca, Geoffroy Hervé, Ong, Derek Yiren, Tran, Thi Mai Huong, Tejo, Ciputra, Chiba, Shunsuke, Gagosz, Fabien
Přispěvatelé: Laboratoire de synthèse organique (DCSO), École polytechnique (X)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Nanyang Technological University, School of Physical and Mathematical Sciences, Division of Chemistry and Biological Chemistry, Nanyang Technological University [Singapour], Department of Chemistry and Biomolecular Sciences University of Ottawa, D'lorio Hall
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Angewandte Chemie International Edition
Angewandte Chemie International Edition, Wiley-VCH Verlag, 2017, 56 (38), pp.11440-11444. ⟨10.1002/anie.201705368⟩
ISSN: 1433-7851
1521-3773
DOI: 10.1002/anie.201705368⟩
Popis: International audience; A protocol for the anti-Markovnikov hydrofunctionalization of alkenes has been developed by the use of a benzyl group as a traceless redox-active hydrogen donor. Under copper catalysis and in the presence of CF3 - or N3 -containing hypervalent iodine reagents, a series of homoallylic alcohol derivatives were hydrofunctionalized regioselectivity. A similar principle was also applied to the hydrofunctionalization of alkenols.
Databáze: OpenAIRE
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