Recent advances on the structure and function of NDH-1: The complex I of oxygenic photosynthesis
| Autor: | Laughlin, Thomas G, Savage, David F, Davies, Karen M |
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| Rok vydání: | 2020 |
| Předmět: |
Chloroplasts
Electron Transport Complex I NADH dehydrogenase-like complex photosynthesis Biophysics Cyanobacteria Cyclic electron flow Vectorial carbonic anhydrase Physical Chemistry Oxygen Electron Transport Protein structure Biochemistry and Cell Biology Photosynthesis Cryo-EM Physical Chemistry (incl. Structural) |
| Zdroj: | Biochimica et biophysica acta. Bioenergetics, vol 1861, iss 11 |
| Popis: | Photosynthetic NADH dehydrogenase-like complex type-1 (a.k.a, NDH, NDH-1, or NDH-1L) is a multi-subunit, membrane-bound oxidoreductase related to the respiratory complex I. Although originally discovered 30years ago, a number of recent advances have revealed significant insight into the structure, function, and physiology of NDH-1. Here, we highlight progress in understanding the function of NDH-1 in the photosynthetic light reactions of both cyanobacteria and chloroplasts from biochemical and structural perspectives. We further examine the cyanobacterial-specific forms of NDH-1 that possess vectorial carbonic anhydrase (vCA) activity and function in the CO2-concentrating mechanism (CCM). We compare the proposed mechanism for the cyanobacterial NDH-1 vCA-activity to that of the DAB (DABs accumulates bicarbonate) complex, another putative vCA. Finally, we discuss both new and remaining questions pertaining to the mechanisms of NDH-1 complexes in light of these recent advances. |
| Databáze: | OpenAIRE |
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