Purification of Thiol Protease Inhibitor from Human Lung Cancer Tissue

Autor:	Okumichi, Tsuneo, Nishiki, Masayuki, Takasugi, Sumiyoshi, Yamane, Motoi, Ezaki, Haruo
Jazyk:	angličtina
Rok vydání:	1984
Předmět:	Human lung cancer Thiol protease inhibitor
Zdroj:	Hiroshima Journal of Medical Sciences. 33(4):801-808
Popis:	It was confirmed that the thiol protease inhibitory activities in human lung cancer extracts were significantly higher than normal lung tissue extracts. Furthermore the thiol protease inhibitor was extracted from human lung cancer tissue and purified by papain-Sepharose and Sephadex G-100 column chromatographies. The purified inhibitor inhibited papain and ficin, and its molecular weight determined by sodium dodecyl sulfate-polyacrylamide gel electrophoresis was about 13,000. This research was funded in part by Grant-in-Aid for Scientific Research, Project 56480213, of the Japanese Ministry of Education.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::18cad4e583be87d90d64b8f998f65ba8 http://ir.lib.hiroshima-u.ac.jp/00038288 Zobrazit plný text záznamu