Prospective associations between hsCRP and GlycA inflammatory biomarkers and depression: The Brazilian longitudinal study of adult health (ELSA-Brasil)

Autor:	Brunoni AR, Salum GA, Hoffmann MS, Goulart AC, Barreto SM, Canhada S, Carvalho AF, Koyanagi A, Calice-Silva V, Lotufo PA, Santos IS, Suemoto CK, Benseñor IM
Rok vydání:	2020
Předmět:	cardiovascular diseases CRP Cohort study Depressive disorder GlycA Persistent depression Psychiatry
Zdroj:	JOURNAL OF AFFECTIVE DISORDERS r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu Fundació Sant Joan de Déu r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu instname
ISSN:	0165-0327
Popis:	Although low-grade inflammation is associated with onset and persistence of depression, most biomarkers display modest predictive effects. GlycA (glycoprotein acetylation) is a unique metabolomic composite of pro-inflammatory acute-phase glycoproteins. We hypothesized that GlycA levels would predict depression incidence, remission and persistence, with higher accuracy than high-sensitivity c-reactive protein (hsCRP). We also explored the additive predictive value of GlycA above and beyond hsCRP.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::17fbb10490d8a7421271b4049e2212e9 http://fundanet.fsjd.org/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=17669 Zobrazit plný text záznamu Full Text from ScienceDirect