Comparison of skeletal muscle mass loss in patients with metastatic colorectal cancer treated with regorafenib or TAS-102

Autor: Bekir Hacioglu, Kostek, Osman, Kurt, Nazmi, Kucukarda, Ahmet, Gokyer, Ali, Ustabasioglu, Fethi Emre, Karatas, Fatih, Tuncbilek, Nermin, Uzunoglu, Sernaz, Bilici, Ahmet, Cicin, Irfan, Erdogan, Bulent
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Web of Science
Popis: Purpose: To assess whether regorafenib and TAS-102 treatments are associated with a change in Skeletal Muscle Area (SMA) as well as to compare Skeletal Muscle Mass (SMM) loss levels between regorafenib and TAS-102 treatments and prognostic significance in the patients with metastatic colorectal cancer (mCRC). Methods: A total of 36 mCRC patients, who received regorafenib or TAS-102 in the third-line and subsequent settings were assessed in the analysis. SMM changes were assessed with CT scans findings, and they were categorized into two groups as SMM-loss (SMM decrease ≥2%) and SMM-stable (SMM change
Databáze: OpenAIRE