Chronic Stress and C-Reactive Protein in Mothers During the First Postpartum Year
| Autor: | Guardino, Christine M, Dunkel Schetter, Christine, Hobel, Calvin J, Gaines Lanzi, Robin, Schafer, Peter, Thorp, John M, Shalowitz, Madeleine U, Community Child Health Network (CCHN) |
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| Rok vydání: | 2017 |
| Předmět: |
Adult
Adolescent Stress Cardiovascular Basic Behavioral and Social Science Medical and Health Sciences Body Mass Index Young Adult Clinical Research Behavioral and Social Science Humans Longitudinal Studies Psychiatry Community Child Health Network Postpartum Period Psychology and Cognitive Sciences C-Reactive Protein Heart Disease Mental Health Good Health and Well Being Socioeconomic Factors inflammation Psychological Female CRP postpartum health Mind and Body |
| Zdroj: | Psychosomatic medicine, vol 79, iss 4 |
| Popis: | ObjectiveElevated levels of C-reactive protein (CRP) are associated with increased risk of cardiovascular and metabolic disease. The current study tested associations between psychosocial stress and CRP in a large sample of women during the first postpartum year.MethodsWe analyzed data collected by the five-site Community Child Health Network study, which studied a predominately poor population. Participants (n = 1206 women; 54% African American, 23% white, 23% Hispanic/Latina) were recruited shortly after the birth of a child. Multiple linear regression analyses tested associations of psychosocial stress in several life domains (financial, neighborhood, family, coparenting, partner relationship, discrimination, and interpersonal violence) with log-transformed CRP concentrations at 6-month and 1-year postpartum.ResultsForty-eight percent of participants showed evidence of elevated CRP (≥3 mg/L) at 6-month postpartum, and 46% had elevated CRP at 12-month postpartum. Chronic financial stress at 1-month postpartum predicted higher levels of CRP at 6- (b = .15, SE = .05, p = .006) and 12-month postpartum (b = .15, SE = .06, p = .007) adjusting for race/ethnicity, income, education, parity, health behaviors, and chronic health conditions, though associations became nonsignificant when adjusted for body mass index.ConclusionsIn this low-income and ethnic/racially diverse sample of women, higher financial stress at 1-month postbirth predicted higher CRP. Study findings suggest that perceived financial stress stemming from socioeconomic disadvantage may be a particular deleterious form of stress affecting maternal biology during the year after the birth of a child. |
| Databáze: | OpenAIRE |
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