The effect of maternal gestational diabetes and hba1c on hypertrophic cardiomyopathy of infants
| Autor: | Rezaie, H., Naghibzadeh-Tahami, A., Mohammadmehdi Bagheri |
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| Zdroj: | Scopus-Elsevier Tehran University Medical Journal, Vol 75, Iss 6, Pp 436-442 (2017) |
| Popis: | Background: The prevalence of gestational diabetes is increasing among pregnant women. It is associated with an increased risk of congenital heart disease, including hypertrophic cardiomyopathy. The aim of this study was to evaluate the effect of maternal diabetes control (based on HbA1c) on their hypertrophic cardiomyopathy in newborns. Methods: This case-control study was performed on 60 neonates born in Afzalipour Hospital (Kerman University of Medical Sciences) from May to November 2014 in two groups of eligible infants using the convenience sampling method. Information about the age, sex, weight, gestational age, maternal age, obstetric history, gestational diabetes through the checklist were collected. Then Doppler echocardiography, M- Mode, Doppler tissue was conducted on two groups. Echocardiographic criteria including ventricular septal thickness and blood HbA1c mothers in both groups were compared. To compare quantitative and qualitative variables between the two groups’ Independent samples t‐test and Chi-square test was used. A significant level of 0.05 was considered in all of the statistical samples and SPSS software, ver. 20 (IBM, Armonk, NY, USA) was used to analyze the data. Results: In this study, the birth weight of infants and the age of mothers did not differ between two groups (Respectively P=0.56, P=0.08) However, HbA1c was significantly higher in the infants of mothers with impaired glucose tolerance test (GTT) (P |
| Databáze: | OpenAIRE |
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