| Autor: |
Aravinda, S, Shamala, N, Roy, Rituparna S, Balaram, P |
| Jazyk: |
angličtina |
| Rok vydání: |
2003 |
| Předmět: |
|
| Zdroj: |
IndraStra Global. |
| ISSN: |
2381-3652 |
| Popis: |
An overview of the use of non-protein amino acids in the design of conformationally well-defined peptides, based on work from the author’s laboratory, is discussed. The crystal structures of several designed oligopeptides illustrate the use alpha-aminoisobutyric acid (Aib) in the construction of helices, D-amino acids in the design of helix termination segments and DPro–Xxx segments for nucleating of beta-hairpin structures. beta- and gamma-amino acid residues have been used to expand the range of designed polypeptide structures. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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