Impaired Recognition and Regulation of Disgust Is Associated with Distinct but Partially Overlapping Patterns of Decreased Gray Matter Volume in the Ventroanterior Insula
| Autor: | Woolley, JD, Strobl, EV, Sturm, VE, Shany-Ur, T, Poorzand, P, Grossman, S, Nguyen, L, Eckart, JA, Levenson, RW, Seeley, WW, Miller, BL, Rankin, KP |
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| Rok vydání: | 2015 |
| Předmět: |
Male
Aging Image Processing Emotions Insula Neuropsychological Tests Medical and Health Sciences Computer-Assisted Clinical Research Behavioral and Social Science Acquired Cognitive Impairment Humans Psychology Family Gray Matter Neurodegeneration Retrospective Studies Aged Cerebral Cortex Psychiatry Psychology and Cognitive Sciences Neurosciences Neurodegenerative Diseases Organ Size Middle Aged Voxel-based morphometry Biological Sciences Magnetic Resonance Imaging humanities Brain Disorders Recognition Frontotemporal Dementia Female Dementia Emotion recognition Facial Recognition Disgust |
| Zdroj: | Biological psychiatry, vol 78, iss 7 Biological Psychiatry, vol 78, iss 7 |
| Popis: | Background The ventroanterior insula is implicated in the experience, expression, and recognition of disgust; however, whether this brain region is required for recognizing disgust or regulating disgusting behaviors remains unknown. Methods We examined the brain correlates of the presence of disgusting behavior and impaired recognition of disgust using voxel-based morphometry in a sample of 305 patients with heterogeneous patterns of neurodegeneration. Permutation-based analyses were used to determine regions of decreased gray matter volume at a significance level p |
| Databáze: | OpenAIRE |
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