Traceability to absorbed-dose-to-water primary standards in dosimetry of brachytherapy sources used for radiotherapy

Autor: Bovi, M., Toni, M. P., Aubineau-Lanièce, I., Bordy, J. -M, Cardoso, J., Chauvenet, B., Gabris, F., Grindborg, J. -E, Guerra, A. S., Kosunen, A., Oliveira, C., Maria Pimpinella, Sander, T., Selbach, H. -J, Sochor, V., Šolc, J., Pooter, J., Dijk, E.
Přispěvatelé: Agenzia Nazionale per le nuove Tecnologie, l’energia e lo sviluppo economico sostenibile = Italian National Agency for New Technologies, Energy and Sustainable Economic Development (ENEA), Laboratoire National Henri Becquerel (LNHB), Département Métrologie Instrumentation & Information (DM2I), Laboratoire d'Intégration des Systèmes et des Technologies (LIST (CEA)), Direction de Recherche Technologique (CEA) (DRT (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Direction de Recherche Technologique (CEA) (DRT (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Laboratoire d'Intégration des Systèmes et des Technologies (LIST (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Département d'instrumentation Numérique (DIN (CEA-LIST)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Instituto Tecnológico e Nuclear, Bundesamt für Eich- und Vermessungswesen [Wien] (BEV), Swedish Radiation Safety Authority, Radiation and Nuclear Safety Authority [Helsinki] (STUK), National Physical Laboratory [Teddington] (NPL), Physikalisch-Technische Bundesanstalt [Braunschweig] (PTB), Czech Metrology Institute, VSL, Dutch Metrology Institute, International Measurement Confederation (IMEKO), European Project: 217257,EC:FP7:GA,FP7-2007-ERANET-4.2.2.2,IMERA-PLUS(2007)
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Zdroj: Scopus-Elsevier
19th IMEKO World Congress 2009 IMEKO XIX World Congress
XIX IMEKO World Congress 2009: Fundamental and Applied Metrology
XIX IMEKO World Congress 2009: Fundamental and Applied Metrology, Sep 2009, Lisbonne, Portugal
Popis: International audience; In the current brachytherapy practice, the procedures to determine the absorbed dose imparted to the patient are affected by an uncertainty higher than in radiotherapy with external beams. That could reduce the success of brachytherapy treatments. Most of the uncertainty is due to a lacking metrology: no absorbed-dose primary standards are so far available to assure direct traceability in dosimetry of brachytherapy sources. This paper outlines the project “Increasing cancer treatment efficacy using 3D brachytherapy”, co-funded in the framework of the project iMERA-Plus according to the Grant Agreement No. 217257 between the European Commission and the European Association of National Metrology Institutes. The aim of the project is to develop methods for the direct measurement of the absorbed dose to water and to extend the use of this reference quantity to brachytherapy dosimetry with an uncertainty on the dose delivered to the target volume less than 5% (k=1) at clinical level. The present project will potentially increase the accuracy and safety of brachytherapy to a level comparable to that typical of radiotherapy with external accelerator beams.
Databáze: OpenAIRE